Clinical trials

Who runs clinical trials?

Universities, hospitals and nonprofits lead about 320,000 of the 461,000 clinical trials registered on ClinicalTrials.gov as of September 2026, about 7 in 10. Drug, device and other companies lead about 113,000, or about 1 in 4; the U.S. National Institutes of Health leads about 7,900. The lead sponsor is the organization responsible for the trial; others may help pay for it.

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Source and date

Data as of
Published

The data

Lead sponsor Clinical trials (all years)
Universities, hospitals and nonprofits 320,285
Companies 113,484
Other governments 11,052
U.S. National Institutes of Health 7,881
Other U.S. federal agencies 4,309
Research networks 3,662
Individuals 459