Clinical trials

Which diseases get the most clinical trials?

About 84,000 clinical trials on ClinicalTrials.gov, roughly 1 in 5 of the 461,000 registered as of September 2026, study cancer or other tumors, more than any other disease group; brain and nerve diseases come next with about 56,000. Groups are the National Library of Medicine's disease categories, and a trial counts in every group its conditions fall under, so the bars add up to more than the total.

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Source and date

Data as of
Published

The data

Disease group Clinical trials (all years)
Cancer and other tumors 84,074
Brain and nerve diseases 56,360
Heart and blood vessel diseases 43,878
Kidney, urinary and genital diseases 40,722
Mental health conditions 40,172
Metabolic diseases, incl. diabetes and obesity 38,644
Lung and airway diseases 37,256
Immune system diseases 36,833
Digestive diseases 33,805
Infections 33,324
Skin and connective tissue diseases 29,415
Hormone (endocrine) diseases 27,334
Pregnancy complications 27,242
Blood diseases 23,309
Bone, joint and muscle diseases 20,599
Inherited and newborn conditions 16,403
Injuries 16,306
Eye diseases 10,785
Mouth and teeth diseases 10,000
Ear, nose and throat diseases 5,820