Food and drug safety

Which side effects are reported most for atorvastatin?

Fatigue (14,402 reports), nausea and diarrhea are the reactions named most often in the roughly 250,000 reports to the FDA, as of June 2026, that list atorvastatin (Lipitor) among a patient's medicines. Muscle pain, a known statin side effect, has about 10,000, and type 2 diabetes about 11,000; statin labels note they can raise blood sugar. A report is not proof the medicine caused the problem: anyone can send one, it lists every medicine the person was taking, and the same case can be reported twice. Reports that the medicine didn't work or was used differently than labeled are left out. Don't stop a medicine without talking to a doctor.

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Source and date

Data as of
Published

The data

Reported reaction Reports to the FDA naming atorvastatin
Fatigue 14,402
Nausea 12,932
Diarrhea 11,591
Shortness of breath 11,588
Type 2 diabetes mellitus 11,281
Pain 10,427
Headache 10,205
Dizziness 10,193
Muscle pain 10,033
Weakness 9,160
Joint pain 8,807
Pain in an arm or leg 8,384
Falls 8,155
Death 7,763
Feeling unwell 7,216