Which NIH institutes spend the most on research?
The National Cancer Institute spent the most of NIH's institutes and centers in fiscal 2025, $6.6 billion of the $42.2 billion in research projects, followed by the allergy and infectious diseases institute ($5.7 billion) and the National Institute on Aging ($4.2 billion). When institutes share a project, each is counted for its part.
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Measure: Funding (dollars). Written from the data below.
- National Cancer Institute (NCI) has the highest figure, $6.6B, followed by National Institute of Allergy and Infectious Diseases (NIAID) ($5.72B) and National Institute on Aging (NIA) ($4.22B).
- NIH Center for Information Technology (CIT) has the lowest figure, $1.34M, followed by Fogarty International Center (FIC) ($69.8M) and National Center for Complementary and Integrative Health (NCCIH) ($140M).
- The highest is 4,942 times the lowest.
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Chartly. “Which NIH institutes spend the most on research?” Chart. Data: NIH RePORTER (National Institutes of Health), https://reporter.nih.gov/ (data as of September 30, 2025). https://chart.ly/charts/nih-funding-by-institute (accessed October 15, 2026).
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The data
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| Institute or center | Funding (dollars) |
|---|---|
| National Cancer Institute (NCI) | 6,598,029,965 |
| National Institute of Allergy and Infectious Diseases (NIAID) | 5,718,469,543 |
| National Institute on Aging (NIA) | 4,216,987,995 |
| National Heart Lung and Blood Institute (NHLBI) | 3,609,995,972 |
| National Institute of General Medical Sciences (NIGMS) | 3,096,132,422 |
| National Institute of Neurological Disorders and Stroke (NINDS) | 2,462,825,732 |
| National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 2,314,146,980 |
| National Institute of Mental Health (NIMH) | 2,115,392,327 |
| NIH Office of the Director (OD) | 2,019,706,327 |
| National Institute of Child Health and Human Development (NICHD) | 1,560,474,826 |
| National Institute on Drug Abuse (NIDA) | 1,516,968,938 |
| National Institute of Environmental Health Sciences (NIEHS) | 869,129,144 |
| National Eye Institute (NEI) | 820,536,838 |
| National Center for Advancing Translational Sciences (NCATS) | 810,157,010 |
| National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | 624,829,491 |
| National Human Genome Research Institute (NHGRI) | 594,597,571 |
| National Institute on Alcohol Abuse and Alcoholism (NIAAA) | 534,859,541 |
| National Institute on Deafness and Other Communication Disorders (NIDCD) | 486,736,177 |
| National Institute on Minority Health and Health Disparities (NIMHD) | 479,436,334 |
| National Institute of Dental and Craniofacial Research (NIDCR) | 472,053,341 |
| National Library of Medicine (NLM) | 469,723,858 |
| National Institute of Biomedical Imaging and Bioengineering (NIBIB) | 388,282,146 |
| National Institute of Nursing Research (NINR) | 169,509,502 |
| National Center for Complementary and Integrative Health (NCCIH) | 140,137,226 |
| Fogarty International Center (FIC) | 69,800,000 |
| NIH Center for Information Technology (CIT) | 1,335,000 |
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