What do Americans die of most often?
In the 12 months through June 2025, heart disease (204 deaths per 100,000 people) and cancer (183) were the leading causes of death in the US, together about 42% of all deaths. Unintentional injuries, which include accidental overdoses, falls and traffic crashes, came third at 56. The numbers are provisional and may change a little as records are completed.
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Source and date
- Data as of
- Published
The data
| Cause of death | Deaths per 100,000 people in a year |
|---|---|
| Heart disease | 203.6 |
| Cancer | 182.9 |
| Unintentional injuries | 55.7 |
| Stroke | 49.8 |
| Chronic lower respiratory diseases | 43.8 |
| Alzheimer disease | 34.5 |
| Diabetes | 28.1 |
| Influenza and pneumonia | 16.7 |
| Kidney disease | 16.5 |
| Chronic liver disease and cirrhosis | 15.4 |