Health

What do Americans aged 45 to 54 die of most often?

In the 12 months through June 2025, cancer (79.6 deaths per 100,000 people aged 45 to 54) and heart disease (72.0) were the leading causes of death in this age group, followed by unintentional injuries (57.9). Chronic liver disease and cirrhosis came fourth, at 20.4. The numbers are provisional.

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Source and date

Data as of
Published

The data

Cause of death Deaths per 100,000 people aged 45 to 54 in a year
Cancer 79.6
Heart disease 72
Unintentional injuries 57.9
Chronic liver disease and cirrhosis 20.4
Suicide 18.7
Diabetes 16
Stroke 12.6
Chronic lower respiratory diseases 6.2
Homicide 5.8
Influenza and pneumonia 5.8